Folate (B9) deficiency

Linked to Vitamin B9 (Folate)

Low folate impairs cell production, causing anaemia and — in pregnancy — birth defects.


Where it shows on the body

Rotate the figure and click a red marker to see the affected area. Internal organs open a 3D organ model.

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Causes

  • Low intake of greens and legumes
  • Pregnancy
  • Alcohol
  • Some medications
  • Malabsorption

Symptoms

  • Fatigue and weakness
  • Mouth sores
  • Shortness of breath
  • Irritability
  • Pale skin

What happens if untreated

  • Megaloblastic anaemia
  • Neural tube defects in a developing baby

Who is most at risk

  • People who could become pregnant
  • Heavy drinkers
  • Those with gut disorders

Prevention & sources

  • Leafy greens, legumes, fortified grains
  • 400 µg folic acid before and in early pregnancy

Correcting it: foods, amounts & timing

Foods that help & safe amounts

  • Leafy greens, legumes and citrus daily
  • Fortified grains
  • 400 µg folic acid daily if you could become pregnant
Time to see benefits

Anaemia symptoms ease over a few weeks as new red cells form.

Symptoms overlap — testing matters

Most deficiency symptoms (fatigue, poor concentration, skin and hair changes) are shared across several nutrients and many unrelated conditions. A symptom on this page is a reason to investigate, not a diagnosis.

A GP can confirm or rule out a deficiency with a blood test and check for underlying causes such as absorption problems. Do not start high-dose supplements on suspicion alone — some nutrients are harmful in excess, and supplementing before testing can mask the underlying result.

VitaWhat is an educational reference only. It is not medical advice and is not authoritative. Always consult a qualified healthcare professional before making changes to your diet, supplements or treatment. See how this content is produced in our editorial policy; report an error via the contact page.